Remus Lupin is one of the Blind Bag characters in LEGO Dimensions 2: The Rise of Enoch, from the Harry Potter franchise.
Remus John Lupin was turned into a werewolf when he was young by Fenrir Greyback. In school he befriended James Potter, Sirius Black, and Peter Pettigrew. They were known for being troublemakers. Lupin tried to hide the fact that he was a werewolf from them, but they realized the pattern in his disappearances and studied to become animaguses (wizards that can turn into animals at will) to be with him.
A young Severus Snape also discovered Lupin's secret when Sirius sent him to Lupin on a Full Moon, but he was rescued by James.
During the first Wizarding War, Lupin was a member of the original Order of the Phoenix.
In Harry Potter's third year he was hired as a Defense Against the Dark Arts teacher at Hogwarts School. He was popular amongst most of the students as he was more adept for teaching than his predecessors, Quirinus Quirrell and Gilderoy Lockhart. He taught the students about Boggarts, Grindylows, and other magical creatures in addition to private lessons with Harry about Dementors.
During the same year, Sirius escaped from Azkaban because he was convicted for the murders of Peter Pettigrew and several muggles. Lupin struggled with whether or not to share this information with Dumbledore, but instead kept it to himself and conducted his own investigation, eventually discovering that Sirius was innocent and that Peter, who had been disguised as Ron Weasley's pet rat Scabbers had survived was to blame for the deaths. He joined Sirius in the Shrieking Shack when Sirius abducted Ron (and Scabbers who was with him). He tried to calm down Harry and Hermione and convince them that he was still on their side. Snape also entered the scene shortly thereafter intent on rescuing the trio, but Harry knocked him out to listen to Lupin and Sirius' explanation uninterrupted.
They revealed that Scabbers was in fact a disguised Peter Pettigrew and, as per Harry's decision, planned to take him back to the school to clear Sirius' name. However, Peter escaped in the chaos when Lupin transformed into a werewolf and Sirius took his dog form to keep him from hurting Harry, Ron, and Hermione.
Lupin left the school shortly after Snape "accidentally" let it slip that he was a werewolf.
Lupin was a later member of the reformed Order of the Phoenix, and married Nymphadora Tonks who had he had a child with, Ted. He fought in the Battle of the Department of Mysteries, the Battle of the Astronomy Tower, and finally in the Battle of Hogwarts where he was killed by Antonin Dolohov and Tonks was murdered by Bellatrix Lestrange. Ted went to live with Tonks' mother.
Lupin's spirit was brought back along with Sirius, Lily, and James' by Harry brings with the Resurrection Stone and they comforted him as he went to surrender to Lord Voldemort.