Irina Spalko is one of the Blind Bag characters in LEGO Dimensions 2: The Rise of Enoch, from the Indiana Jones franchise.
Colonel Doctor Irina Spalko is the main enemy in Kingdom of the Crystal Skull and is usually seen carrying a rapier. She has the rank of Colonel Doctor and was referred by General Ross as "Stalin's fair-haired girl". She was killed when she returned the Crystal Skull to the temple, causing the 13 ( 3 in the set) Crystal Skeletons to form into a single alien being, saying that she could have all the knowledge of the world and beyond. Spalko demanded to know everything, so the essence of knowledge was bestowed upon her. However, it was too much for her, and she spontaneously combusted, disintegrated, and her remains, along with the Russian soldiers, were sucked into an interdimensional portal.